Article
A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes.
Diabetes - 1 Sept 2011
Chung Chia-Min, Lin Tsung-Hsien, Chen Jaw-Wen, Leu Hsin-Bang, Yang Hsin-Chou, Ho Hung-Yun, Ting Chih-Tai, Sheu Sheng-Hsiung, Tsai Wei-Chuan, Chen Jyh-Hong, Lin Shing-Jong, Chen Yuan-Tsong, Pan Wen-Harn
Abstract excerpt
OBJECTIVE: The plasma adiponectin level, a potential upstream and internal facet of metabolic and cardiovascular diseases, has a reasonably high heritability. Whether other novel genes influence the variation in adiponectin level and the roles of these genetic variants on subsequent clinical outcomes has not been thoroughly investigated. Therefore, we aimed not only to identify genetic variants modulating plasma...
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