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Article

Androgen Modulation of Coregulator Expression in Prostate Cancer Cells

23 Jan 2009

Abstract excerpt

Aberrant coregulator expression that occurs during prostate cancer (PCa) progression correlates with poor prognosis and aggressive disease. This has been attributed to the ability to regulate androgen receptor-mediated transcription. We have shown previously that the androgenic milieu regulates the expression of the coactivators p300 and FHL2, with severe consequences for PCa cell proliferation and androgen...

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Identifiers

PMID: 19164447
DOI: 10.1210/me.2008-0363

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