Article
SAT-1 -1415T/C polymorphism and susceptibility to schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 17 Mar 2009
Bermudo-Soriano Carlos Riaza, Vaquero-Lorenzo Concepcion, Diaz-Hernandez Montserrat, Perez-Rodriguez M Mercedes, Fernandez-Piqueras Jose, Saiz-Ruiz Jeronimo, Baca-Garcia Enrique
Abstract excerpt
Patients suffering from psychosis show increased blood and fibroblast total polyamine levels. Spermidine/spermine N1-acetyltransferase (SSAT-1) and its coding gene (SAT-1) are the main factors regulating polyamine catabolism. The aim of the present study was to examine the association between the SAT-1 -1415T/C single nucleotide polymorphism (SNP) and schizophrenia. A case-control design was used in order to...
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