Article
Saitohin polymorphism and executive dysfunction in schizophrenia.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Oct 2012
Bosia Marta, Buonocore Mariachiara, Guglielmino Carmelo, Pirovano Adele, Lorenzi Cristina, Marcone Alessandra, Bramanti Placido, Cappa Stefano F, Aguglia Eugenio, Smeraldi Enrico, Cavallaro Roberto
Abstract excerpt
Saitohin (STH) is an intronless gene nested within the human tau gene, which contains a single nucleotide polymorphism (A/G), suggested to be involved in the physiopathology and clinical course of several neurodegenerative and neuropsychiatric diseases. Recently, an association between this polymorphism and frontal hypoperfusion and clinical prognosis in frontotemporal dementia was reported. The present study...
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