Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Positive association between SAT-1 -1415T/C polymorphism and anxiety.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2009

Vaquero-Lorenzo Concepción, Riaza Bermudo-Soriano Carlos, Perez-Rodriguez M Mercedes, Diaz-Hernandez Montserrat, López-Castromán Jorge, Fernandez-Piqueras Jose, Saiz-Ruiz Jeronimo, Baca-Garcia Enrique

Abstract excerpt

Limbic glutamatergic neurotransmission plays a pivotal role in the pathogenesis of anxiety disorders. Polyamines modulate the activity of several ionotropic glutamate receptors and have been involved in the regulation of fear-conditioning response. Spermidine/spermine N1-acetyltransferase (SSAT-1) is the main enzyme regulating polyamine catabolism. The aim of the present study was to examine the association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyltransferases
Share to Anxiety

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Sex Factors

Source

Identifiers

PMID: 18759322
DOI: 10.1002/ajmg.b.30850

Genes

SAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Positive association between SAT-1 -1415T/C polymorphism and anxiety.PMID 18759322Read ↗

SAT-1 -1415T/C polymorphism and susceptibility to schizophrenia.Semantic proximity Read ↗

Association of polyaminergic loci with anxiety, mood disorders, and attempted suicide.Semantic proximity Read ↗

Putative association between the -1415 T/C polymorphism of spermidine/spermine N1-acetyltransferase (SSAT1) gene and alcohol use disorders in women and men.Semantic proximity Read ↗

Association between anxiety and non-coding genetic variants of the galanin neuropeptide.Semantic proximity Read ↗

Further evidence for genetic variation at the serotonin transporter gene SLC6A4 contributing toward anxiety.Semantic proximity Read ↗

Rare Variant in the SLC6A2 Encoding a Norepinephrine Transporter Is Associated with Elite Athletic Performance in the Polish Population.Semantic proximity Read ↗

Implication of SSAT by gene expression and genetic variation in suicide and major depression.Semantic proximity Read ↗

Variation in SLC1A1 is related to combat-related posttraumatic stress disorder.Semantic proximity Read ↗

Promoter variants of the cannabinoid receptor 1 gene (CNR1) in interaction with 5-HTTLPR affect the anxious phenotype.Semantic proximity Read ↗

SLC1A2 rs3794087 variant and risk for migraine.Semantic proximity Read ↗

A family-based study of Indian subjects from Kolkata reveals allelic association of the serotonin transporter intron-2 (STin2) polymorphism and attention-deficit-hyperactivity disorder (ADHD).Semantic proximity Read ↗

The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.