Article
Identification and characterization of spermidine/spermine N1-acetyltransferase promoter variants in suicide completers.
Biological psychiatry - 1 Sept 2009
Fiori Laura M, Mechawar Naguib, Turecki Gustavo
Abstract excerpt
BACKGROUND: We have previously shown that the expression of spermidine/spermine N1-acetyltransferase (SAT1) is decreased in the brain Brodmann areas (BA)4, BA8/9, and BA11 of suicide completers and found an association between rs6526342, a SAT1 promoter single nucleotide polymorphism (SNP), with suicide completion (1). METHODS: We genotyped 18 promoter polymorphisms in SAT1 in a French-Canadian population. The...
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