Article
Coilin is essential for Cajal body organization in Drosophila melanogaster.
Molecular biology of the cell - 1 Mar 2009
Liu Ji-Long, Wu Zheng'an, Nizami Zehra, Deryusheva Svetlana, Rajendra T K, Beumer Kelly J, Gao Hongjuan, Matera A Gregory, Carroll Dana, Gall Joseph G
Abstract excerpt
Cajal bodies (CBs) are nuclear organelles that occur in a variety of organisms, including vertebrates, insects, and plants. They are most often identified with antibodies against the marker protein coilin. Because the amino acid sequence of coilin is not strongly conserved evolutionarily, coilin orthologues have been difficult to recognize by homology search. Here, we report the identification of Drosophila...
Topics
- Aging
- Amino Acid Sequence
- Animals
- Cell Cycle
- Coiled Bodies
- Conserved Sequence
- Drosophila melanogaster
- Female
- Histones
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Nuclear Proteins