Article
Oligoclonal CD8 lymphocytes from persons with asymptomatic human immunodeficiency virus (HIV) type 1 infection inhibit HIV-1 replication.
The Journal of infectious diseases - 1 Oct 1995
Toso J F, Chen C H, Mohr J R, Piglia L, Oei C, Ferrari G, Greenberg M L, Weinhold K J
Abstract excerpt
CD8 lymphocytes from asymptomatic human immunodeficiency virus (HIV) type 1-infected patients can suppress virus production from infected CD4 cells. Suppressive activity is separate and distinct from cytotoxic T lymphocyte (CTL) reactivities and is likely mediated by a soluble factor(s). The majority of HIV-1 suppression studies have been done in the context of bulk CD8 cell cultures. In this study, viral...
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