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Article

Relationship between genetic variants in myocardial sodium and potassium channel genes and QT interval duration in diabetics: the Diabetes Heart Study.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc - 1 Jan 2009

Lehtinen Allison B, Daniel Kurt R, Shah Sidharth A, Nelson Matthew R, Ziegler Julie T, Freedman Barry I, Carr J Jeffrey, Herrington David M, Langefeld Carl D, Bowden Donald W

Abstract excerpt

BACKGROUND: Genetic variants in myocardial sodium and potassium channel genes are associated with prolonged QT interval and increased risk of sudden death. It is unclear whether these genetic variants remain relevant in subjects with underlying conditions such as diabetes that are associated with prolonged QT interval. METHODS: We tested single nucleotide polymorphisms (SNPs) in five candidate genes for...

Topics

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Electrocardiography
KCNQ1 Potassium Channel
KCNQ2 Potassium Channel
Long QT Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Muscle Proteins

NAV1.5 Voltage-Gated Sodium Channel

Sodium Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 19149796
DOI: 10.1111/j.1542-474X.2008.00276.x
PMCID: PMC3650725

Genes

KCNQ1
SCN5A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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