Article
Phenotypic characterization of the Komeda miniature rat Ishikawa, an animal model of dwarfism caused by a mutation in Prkg2.
Comparative medicine - 1 Dec 2008
Tsuchida Atsuko, Yokoi Norihide, Namae Misako, Fuse Masanori, Masuyama Taku, Sasaki Masashi, Kawazu Shoji, Komeda Kajuro
Abstract excerpt
The Komeda miniature rat Ishikawa (KMI) is a spontaneous animal model of dwarfism caused by a mutation in Prkg2, which encodes cGMP-dependent protein kinase type II (cGKII). This strain has been maintained as a segregating inbred strain for the mutated allele mri. In this study, we characterized the phenotype of the KMI strain, particularly growth traits, craniofacial measurements, and organ weights. The...
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