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Article

Multiple measures of functionality exhibit progressive decline in a parallel, stochastic fashion in Drosophila Sod2 null mutants.

Biogerontology - 1 Oct 2009

Piazza Nicole, Hayes Michael, Martin Ian, Duttaroy Atanu, Grotewiel Mike, Wessells Robert

Abstract excerpt

Oxidative damage has been proposed as an important factor in the progression of pathological and non-pathological age-related functional declines. Here, we examine functional deterioration in short-lived flies mutant for the mitochondrial antioxidant Manganese Superoxide Dismutase (Sod2). We find that the decline of several functional measures of aging occurs, in an accelerated fashion, in Sod2 mutants. Olfactory...

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Identifiers

PMID: 19148770
DOI: 10.1007/s10522-008-9210-2
PMCID: PMC2800787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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