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Article

A Sod2 null mutation confers severely reduced adult life span in Drosophila.

Genetics - 1 Dec 2003

Duttaroy Atanu, Paul Anirban, Kundu Mukta, Belton Amy

Abstract excerpt

A null mutation for the Sod2 gene, Sod2n283, was obtained in Drosophila melanogaster. Homozygous Sod2 null (Sodn283/Sodn283) adult flies survive up to 24 hr following eclosion, a phenotype reminiscent of mice, where Sod2-/- progeny suffer neonatal lethality. Sodn283/+ heterozygotes are sensitive to oxidative stress induced by paraquat treatment.

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Identifiers

PMID: 14704205
DOI: 10.1093/genetics/165.4.2295
PMCID: PMC1462872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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