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Article

Mitochondrial superoxide radicals differentially affect muscle activity and neural function.

Genetics - 1 Sept 2009

Godenschwege Tanja, Forde Renée, Davis Claudette P, Paul Anirban, Beckwith Kristopher, Duttaroy Atanu

Abstract excerpt

Cellular superoxide radicals (O(2)(-)) are mostly generated during mitochondrial oxygen metabolism. O(2)(-) serves as the raw material for many reactive oxygen species (ROS) members like H(2)O(2) and OH(.-) radicals following its catalysis by superoxide dismutase (SOD) enzymes and also by autocatalysis (autodismutation) reactions. Mitochondrial ROS generation could have serious implications on degenerative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19546321
DOI: 10.1534/genetics.109.103515
PMCID: PMC2746142

Genes

SOD2

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