Article
Lack of association between the TNF-alpha -308 (G/A) genetic polymorphism and periodontal disease in Brazilians.
Brazilian oral research - 1 Jan 2000
Menezes Natascha Giovannetti de, Colombo Ana Paula Vieira
Abstract excerpt
This study evaluated the frequency of the tumor necrosis factor-alpha (TNF-alpha) -308 G/A polymorphism in Brazilians with periodontal health (PH = 51), chronic periodontitis (CP = 74) and generalized aggressive periodontitis (GAgP = 38). Human DNA was obtained from mouthwash samples and TNF-alpha genotyping was performed by PCR and RFLP analyses. Differences in clinical and genetic parameters among groups were...
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