Article
Lack of association between the TNF-α-1031genotypes and generalized aggressive periodontitis disease.
Cellular and molecular biology (Noisy-le-Grand, France) - 30 Sept 2016
Darvishi E, Aziziaram Z, Yari K, Bagheri Dehbaghi M, Kahrizi D, Karim H, Vaziri S, Zargooshi J, Ghadiri K, Muhammadi S, Kazemi E, Moradi M T, Shokrinia M, Mohammadi N
Abstract excerpt
Periodontal disease is one of the most prevalent inflammatory illnesses and is a main cause of tooth loss in human population. Tumor necrosis factor-α (TNF-α) gene is one of pro-inflammatory cytokines which has important role in pathogenesis of periodontal disease. The main purpose of this study is to determine genotype abundance of TNF-α-1031 gene in both groups of patients and controls, and also investigation...
Topics
- Adult
- Aggressive Periodontitis
- Alleles
- Case-Control Studies
- DNA
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans