Article
Analysis of IL-1A(-889) and TNFA(-308) gene polymorphism in Brazilian patients with generalized aggressive periodontitis.
European cytokine network - 1 Sept 2007
Maria de Freitas Nívea, Imbronito Ana Vitória, Neves Adriana Costa, Nunes Fábio Daumas, Pustiglioni Francisco Emilio, Lotufo Roberto Fraga Moreira
Abstract excerpt
Generalized aggressive periodontitis (GAP) comprises a group of periodontal diseases characterized by the rapid destruction of periodontal tissues which affect young individuals who generally present no systemic disorders. Polymorphisms in the interleukin-1 (IL-1) and tumor necrosis factor-alpha...
Topics
- Acute Disease
- Adult
- Brazil
- Case-Control Studies
- DNA
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Immunologic Factors
- Interleukin-1alpha
- Male
- Periodontal Attachment Loss
- Periodontitis
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single Nucleotide