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Article

Analysis of IL-1A(-889) and TNFA(-308) gene polymorphism in Brazilian patients with generalized aggressive periodontitis.

European cytokine network - 1 Sept 2007

Maria de Freitas Nívea, Imbronito Ana Vitória, Neves Adriana Costa, Nunes Fábio Daumas, Pustiglioni Francisco Emilio, Lotufo Roberto Fraga Moreira

Abstract excerpt

Generalized aggressive periodontitis (GAP) comprises a group of periodontal diseases characterized by the rapid destruction of periodontal tissues which affect young individuals who generally present no systemic disorders. Polymorphisms in the interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) genes have been associated with an increased severity of chronic periodontitis. The objective of the...

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PMID: 17823082
DOI: 10.1684/ecn.2007.0100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of IL-1A(-889) and TNFA(-308) gene polymorphism in Brazilian patients with generalized aggressive periodontitis.PMID 17823082Read ↗

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