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Article

A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster

14 Jan 2009

Abstract excerpt

We have identified an intergenic transcriptional activity that is located between the human HOXA1 and HOXA2 genes, shows myeloid-specific expression, and is up-regulated during granulocytic differentiation. The novel gene, termed HOTAIRM1 (HOX antisense intergenic RNA myeloid 1), is transcribed antisense to the HOXA genes and originates from the same CpG island that embeds the start site of HOXA1. The transcript...

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PMID: 19144990
DOI: 10.1182/blood-2008-06-162164

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