Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polyunsaturated fatty acids modulate the effect of TCF7L2 gene variants on postprandial lipemia.

The Journal of nutrition - 1 Mar 2009

Warodomwichit Daruneewan, Arnett Donna K, Kabagambe Edmond K, Tsai Michael Y, Hixson James E, Straka Robert J, Province Michael, An Ping, Lai Chao-Qiang, Borecki Ingrid, Ordovas Jose M

Abstract excerpt

The transcription factor 7-like 2 (TCF7L2) has been recently associated with diabetes risk, and it may exert its effect through metabolic syndrome (MetS)-related traits and be subjected to modification by environmental factors. We investigated the effect of single nucleotide polymorphisms (SNP), rs7903146 and rs12255372, within the TCF7L2 locus on postprandial lipemia and other MetS-related traits and their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet
Share to Aged, 80 and over
Share to Fatty Acids, Unsaturated
Share to Gene Expression Regulation
Share to Hyperlipidemias
Share to Postprandial Period
Share to TCF Transcription Factors
Share to Transcription Factor 7-Like 2 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 19141698
DOI: 10.3945/jn.108.096461
PMCID: PMC2714378

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polyunsaturated fatty acids modulate the effect of TCF7L2 gene variants on postprandial lipemia.PMID 19141698Read ↗

Pleiotropic effects of TCF7L2 gene variants and its modulation in the metabolic syndrome: from the LIPGENE study.Semantic proximity Read ↗

Effects of rs7903146 variation in the Tcf7l2 gene in the lipid metabolism of three different populations.Semantic proximity Read ↗

Dietary saturated fat, gender and genetic variation at the TCF7L2 locus predict the development of metabolic syndrome.Semantic proximity Read ↗

The Protective Effect of Transcription Factor 7-Like 2 Risk Allele rs7903146 against Elevated Fasting Plasma Triglyceride in Type 2 Diabetes: A Meta-Analysis.Semantic proximity Read ↗

Genetic variations at the lipoprotein lipase gene influence plasma lipid concentrations and interact with plasma n-6 polyunsaturated fatty acids to modulate lipid metabolism.Semantic proximity Read ↗

Interaction between the TCF7L2 gene and dietary intake on metabolic syndrome risk factors among Saudi Arabian adultsSemantic proximity Read ↗

Glucose tolerance and free fatty acid metabolism in adults with variations in TCF7L2 rs7903146.Semantic proximity Read ↗

Homozygous carriers of the TCF7L2 rs7903146 T-allele show altered postprandial response in triglycerides and triglyceride-rich lipoproteins.Semantic proximity Read ↗

Interaction between TCF7L2 polymorphism and dietary fat intake on high density lipoprotein cholesterol.Semantic proximity Read ↗

Changes in triglyceride-rich lipoprotein particle profiles in response to one-week on a low fat or Mediterranean diet by TCF7L2 rs7903146 genotype: a randomized crossover dietary intervention trialSemantic proximity Read ↗

Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome.Semantic proximity Read ↗

Dietary Macronutrient Intake May Influence the Effects of TCF7L2 rs7901695 Genetic Variants on Glucose Homeostasis and Obesity-Related Parameters: A Cross-Sectional Population-Based Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.