Article
Effects of rs7903146 variation in the Tcf7l2 gene in the lipid metabolism of three different populations.
PloS one - 1 Jan 2012
Perez-Martinez Pablo, Perez-Caballero Ana I, Garcia-Rios Antonio, Yubero-Serrano Elena M, Camargo Antonio, Gomez-Luna Maria J, Marin Carmen, Gomez-Luna Purificacion, Dembinska-Kiec Aldona, Rodriguez-Cantalejo Fernando, Tinahones Francisco J, Roche Helen M, Perez-Jimenez Francisco, Lopez-Miranda Jose, Delgado-Lista Javier
Abstract excerpt
BACKGROUND: TCF7L2 rs7903146 is an important genetic factor predicting type 2 diabetes (T2DM) which has also been linked to higher cardiovascular risk. To date, there is little information about the additional impact of this single nucleotide polymorphism (SNP) beyond glucose metabolism. METHODOLOGY/PRINCIPAL FINDINGS: We studied whether rs7903146 influenced postprandial lipid metabolism in three different...
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