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Article

Co-localization of constituents of the dengue virus translation and replication machinery with amphisomes

13 Jan 2009

Abstract excerpt

Infections with dengue virus (DENV) are a significant public health concern in tropical and subtropical regions. However, little detail is known about how DENV interacts with the host-cell machinery to facilitate its translation and replication. In DENV-infected HepG2 cells, an increase in the level of LC3-II (microtubule-associated protein 1 light chain 3 form II), the autophagosomal membrane-bound form of LC3,...

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PMID: 19141455
DOI: 10.1099/vir.0.005355-0

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