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Article

Aggresomes and Autophagy Generate Sites for Virus Replication

12 May 2006

Abstract excerpt

The replication of many viruses is associated with specific intracellular compartments called virus factories or virioplasm. These are thought to provide a physical scaffold to concentrate viral components and thereby increase the efficiency of replication. The formation of virus replication sites often results in rearrangement of cellular membranes and reorganization of the cytoskeleton. Similar rearrangements...

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Identifiers

PMID: 16690857
DOI: 10.1126/science.1126766

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