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Article

A role for autophagolysosomes in dengue virus 3 production in HepG2 cells

13 Apr 2009

Abstract excerpt

We have recently proposed that amphisomes act as a site for translation and replication of dengue virus (DENV)-2 and that DENV-2 entry and replication are linked through an ongoing association with membranes of an endosomal-autophagosomal lineage. In this report, we present the results of an investigation into the interaction between DENV-3 and the autophagy machinery. Critically, treatment with the lysosomal...

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PMID: 19264601
DOI: 10.1099/vir.0.007914-0

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