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Article

Oxidative stress may enhance the malignant potential of human hepatocellular carcinoma by telomerase activation

5 Jun 2009

Abstract excerpt

BACKGROUND/AIMS: Continuous oxidative stress (OS) plays an important role in the progression of chronic liver diseases and hepatocarcinogenesis through telomere shortening in hepatocytes. However, it has not been established how the OS influences the progression of human hepatocellular carcinomas (HCCs). We examined the correlations of OS with telomere length of cancer cells, telomerase activity and other...

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Share to Cancer-related molecular mechanisms research
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PMID: 19141026
DOI: 10.1111/j.1478-3231.2008.01963.x

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