Article
Oxidative Stress and Epigenetic Instability in Human Hepatocarcinogenesis
1 Jan 2013
Abstract excerpt
Hepatocellular carcinoma (HCC) is a major cause of cancer death, and its development is influenced by the status of inflammation and oxidative stress in the liver. Although oxidative stress might induce genetic changes and play a role in HCC development, many epigenetic alterations have also been reported in this type of tumor, suggesting the importance of epigenetic instability in hepatocarcinogenesis....
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