Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomere length variation in tumor cells and cancer-associated fibroblasts: potential biomarker for hepatocellular carcinoma.

The Journal of pathology - 1 Dec 2017

Ma Li-Jie, Wang Xiao-Ying, Duan Meng, Liu Long-Zi, Shi Jie-Yi, Dong Liang-Qing, Yang Liu-Xiao, Wang Zhi-Chao, Ding Zhen-Bin, Ke Ai-Wu, Cao Ya, Zhang Xiao-Ming, Zhou Jian, Fan Jia, Gao Qiang

Abstract excerpt

The role of telomere dysfunction and aberrant telomerase activities in hepatocellular carcinoma (HCC) has been overlooked for many years. This study aimed to delineate the variation and prognostic value of telomere length in HCC. Telomere-specific fluorescence in situ hybridization (FISH) and qPCR were used to evaluate telomere length in HCC cell lines, tumor tissues, and isolated non-tumor cells within the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-Associated Fibroblasts
Share to Neoplasm Recurrence, Local

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proportional Hazards Models

Share to Telomerase

Share to Telomere

Share to Telomere Homeostasis

Share to Telomere Shortening

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 28833123
DOI: 10.1002/path.4961
PMCID: PMC5725724

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telomere length variation in tumor cells and cancer-associated fibroblasts: potential biomarker for hepatocellular carcinoma.PMID 28833123Read ↗

Telomere length is key to hepatocellular carcinoma diversity and telomerase addiction is an actionable therapeutic targetSemantic proximity Read ↗

Significance of TERT Genetic Alterations and Telomere Length in Hepatocellular CarcinomaSemantic proximity Read ↗

Telomere Length Changes in Cancer: Insights on Carcinogenesis and Potential for Non-Invasive Diagnostic StrategiesSemantic proximity Read ↗

Telomere length in hepatocellular carcinoma and paired adjacent non-tumor tissues by quantitative PCR.Semantic proximity Read ↗

Clinicopathological characteristics of TERT promoter mutation and telomere length in hepatocellular carcinoma.Semantic proximity Read ↗

Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatomaSemantic proximity Read ↗

Significant SNPs Related to Telomere Length and Hepatocellular Carcinoma Risk in Chronic Hepatitis B CarriersSemantic proximity Read ↗

Expression of Cellular and Extracellular TERRA, TERC and TERT in Hepatocellular CarcinomaSemantic proximity Read ↗

Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma.Semantic proximity Read ↗

Reduction of telomeric repeats as a possible predictor for development of hepatocellular carcinoma: Convenient evaluation by slot-blot analysisSemantic proximity Read ↗

Telomere Length in Patients with Alcohol-Associated Liver Disease: A Brief ReportSemantic proximity Read ↗

Cause-specific telomere factors deregulation in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.