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Article

MRI correlates of cognitive decline in CADASIL: a 7-year follow-up study.

Neurology - 13 Jan 2009

Liem M K, Lesnik Oberstein S A J, Haan J, van der Neut I L, Ferrari M D, van Buchem M A, Middelkoop H A M, van der Grond J

Abstract excerpt

BACKGROUND: Cognitive decline is one of the clinical hallmarks of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a cerebrovascular disease caused by NOTCH3 mutations. In this 7-year follow-up study, we aimed to determine whether there are associations between the different radiologic hallmarks in CADASIL and decline in specific cognitive domains. METHODS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19139365
DOI: 10.1212/01.wnl.0000339038.65508.96

Genes

NOTCH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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