Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical correlates of longitudinal MRI changes in CADASIL.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Jul 2019

Ling Yifeng, De Guio François, Jouvent Eric, Duering Marco, Hervé Dominique, Guichard Jean Pierre, Godin Ophélia, Dichgans Martin, Chabriat Hugues

Abstract excerpt

Previous studies showed that various types of cerebral lesions, as assessed on MRI, largely contribute to the clinical severity of CADASIL. However, the clinical impact of longitudinal changes of classical markers of small vessel disease on conventional MRI has been only poorly investigated. One hundred sixty NOTCH3 mutation carriers (mean age ± SD, 49.8 ± 10.9 years) were followed over three years. Validated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrophy
Share to CADASIL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dementia

Share to Disease Progression

Share to Longitudinal Studies

Share to Magnetic Resonance Imaging

Share to Receptor, Notch3

Share to Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 29400120
DOI: 10.1177/0271678X18757875
PMCID: PMC6668524

Genes

NOTCH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical correlates of longitudinal MRI changes in CADASIL.PMID 29400120Read ↗

MRI correlates of cognitive decline in CADASIL: a 7-year follow-up study.Semantic proximity Read ↗

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: progression of MR abnormalities in prospective 7-year follow-up study.Semantic proximity Read ↗

Sex Differences in the Clinical and Imaging Characteristics of Korean CADASIL Patients: A Korean Nationwide Retrospective StudySemantic proximity Read ↗

Genotype-phenotype correlations in a Scottish CADASIL cohort and comparison with sporadic small vessel disease.Semantic proximity Read ↗

Effect of NOTCH3 EGFr Group, Sex, and Cardiovascular Risk Factors on CADASIL Clinical and Neuroimaging Outcomes.Semantic proximity Read ↗

Patterns of MRI lesions in CADASIL.Semantic proximity Read ↗

Lacunar infarcts are the main correlate with cognitive dysfunction in CADASIL.Semantic proximity Read ↗

<i>NOTCH3</i> variants are common in the general population and associated with stroke and vascular dementia: an analysis of 200,000 participantsSemantic proximity Read ↗

Cerebral microbleeds in CADASIL.Semantic proximity Read ↗

Clinical significance of cerebral microbleeds locations in CADASIL with R544C NOTCH3 mutation.Semantic proximity Read ↗

Iron leakage owing to blood-brain barrier disruption in small vessel disease CADASIL.Semantic proximity Read ↗

Heritability of MRI Lesion Volume in CADASILSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.