Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amyotrophic lateral sclerosis-plus syndrome with TAR DNA-binding protein-43 pathology.

Archives of neurology - 1 Jan 2009

McCluskey Leo F, Elman Lauren B, Martinez-Lage Maria, Van Deerlin Vivianna, Yuan Wuxing, Clay Dana, Siderowf Andrew, Trojanowski John Q

Abstract excerpt

BACKGROUND: Amyotrophic lateral sclerosis (ALS)-Plus syndromes meet clinical criteria for ALS but also include 1 or more additional features such as dementia, geographic clustering, extrapyramidal signs, objective sensory loss, autonomic dysfunction, cerebellar degeneration, or ocular motility disturbance. METHODS: We performed a whole-brain and spinal cord pathologic analysis in a patient with an ALS-Plus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to Dementia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Fatal Outcome

Share to Inclusion Bodies

Share to Motor Neurons

Share to Ocular Motility Disorders

Share to Pyramidal Tracts

Source

Open in PubMed Open full text

Identifiers

PMID: 19139310
DOI: 10.1001/archneur.66.1.121
PMCID: PMC2702763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amyotrophic lateral sclerosis-plus syndrome with TAR DNA-binding protein-43 pathology.PMID 19139310Read ↗

TDP-43 proteinopathies: a new wave of neurodegenerative diseasesSemantic proximity Read ↗

ALS-Plus syndrome: non-pyramidal features in a large ALS cohort.Semantic proximity Read ↗

Pathology and genetics of frontotemporal lobar degeneration: an update.Semantic proximity Read ↗

Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.Semantic proximity Read ↗

Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.Semantic proximity Read ↗

Stages of pTDP-43 pathology in amyotrophic lateral sclerosis.Semantic proximity Read ↗

TARDBP mutations in motoneuron disease with frontotemporal lobar degeneration.Semantic proximity Read ↗

Different clinical and neuropathologic phenotypes of familial ALS with A315E TARDBP mutation.Semantic proximity Read ↗

Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases.Semantic proximity Read ↗

The frontotemporal dementia-motor neuron disease continuum.Semantic proximity Read ↗

TAR DNA-binding protein 43 pathology in a case clinically diagnosed with facial-onset sensory and motor neuronopathy syndrome: an autopsied case report and a review of the literature.Semantic proximity Read ↗

Nuclear TAR DNA binding protein 43 expression in spinal cord neurons correlates with the clinical course in amyotrophic lateral sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.