The gene DIS2S1 is essential in Saccharomyces cerevisiae and is involved in glycogen phosphorylase activation.

doi:10.1007/BF00309593

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Article

The gene DIS2S1 is essential in Saccharomyces cerevisiae and is involved in glycogen phosphorylase activation.

Current genetics - 1 May 1991

Clotet J, Posas F, Casamayor A, Schaaff-Gerstenschläger I, Ariño J

Abstract excerpt

S. cerevisiae gene DIS2S1, which codes for a protein very similar to the catalytic subunit of mammalian protein phosphatase 1, was disrupted "in vitro". Diploid yeast cells were transformed and sporulated. Tetrad analysis demonstrated that disruption of DIS2S1 is lethal for the cell. Glycogen pho...

Topics

Catalysis
Diploidy
Enzyme Activation
Genes, Fungal
Glucose
Glycogen Synthase
Mutation
Phosphorylases
Restriction Mapping
Saccharomyces cerevisiae

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