Article
Glycogen synthesis in the absence of glycogenin in the yeast Saccharomyces cerevisiae.
FEBS letters - 18 Jul 2005
Torija María-Jesús, Novo Maite, Lemassu Anne, Wilson Wayne, Roach Peter J, François Jean, Parrou Jean-Luc
Abstract excerpt
In eukaryotic cells, glycogenin is a self-glucosylating protein that primes glycogen synthesis. In yeast, the loss of function of GLG1 and GLG2, which encode glycogenin, normally leads to the inability of cells to synthesize glycogen. In this report, we show that a small fraction of colonies from glg1glg2 mutants can switch on glycogen synthesis to levels comparable to wild-type strain. The occurrence of glycogen...
Topics
- Culture Media
- Epigenesis, Genetic
- Gene Silencing
- Glucose
- Glucosyltransferases
- Glycogen
- Glycogen Synthase
- Glycoproteins
- Iodine
- Magnetic Resonance Spectroscopy
- Mutation
- Phenotype
- Plasmids
- Protons
- Saccharomyces cerevisiae