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Article

Superoxide dismutase is regulated by LAMMER kinase in Drosophila and human cells.

Free radical biology & medicine - 15 Mar 2009

James Brian P, Staatz William D, Wilkinson Sarah T, Meuillet Emmanuelle, Powis Garth

Abstract excerpt

LAMMER kinases (also known as CDC-2-like or CLKs) are a family of dual specificity serine/threonine protein kinases that are found in all sequenced eukaryotic genomes. In the fission yeast, Schizosaccharomyces pombe, the LAMMER kinase gene, Lkh1, positively regulates the expression of the antioxidant defense genes, superoxide dismutase 1 (sod1+, CuZn-SOD) and catalase (ctt1+, CAT). We have shown that mutations in...

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Identifiers

PMID: 19135146
DOI: 10.1016/j.freeradbiomed.2008.12.012
PMCID: PMC2699669

Genes

SOD1
CAT
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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