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Article

FGF20 and Parkinson's disease: No evidence of association or pathogenicity via α‐synuclein expression

9 Jan 2009

Abstract excerpt

Genetic variation in fibroblast growth factor 20 (FGF20) has been associated with risk of Parkinson's disease (PD). Functional evidence suggested the T allele of one SNP, rs12720208 C/T, altered PD risk by increasing FGF20 and alpha-synuclein protein levels. Herein we report our association study of FGF20 and PD risk in four patient-control series (total: 1,262 patients and 1,881 controls), and measurements of...

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PMID: 19133659
DOI: 10.1002/mds.22442

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