FGF20 rs12720208 SNP and microRNA-433 variation: no association with Parkinson's disease in Spanish patients.

doi:10.1016/j.neulet.2010.05.019

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Article

FGF20 rs12720208 SNP and microRNA-433 variation: no association with Parkinson's disease in Spanish patients.

Neuroscience letters - 19 Jul 2010

de Mena Lorena, Cardo Lucía F, Coto Eliecer, Miar Ana, Díaz Marta, Corao Ana I, Alonso Belén, Ribacoba René, Salvador Carlos, Menéndez Manuel, Morís Germán, Alvarez Victoria

Abstract excerpt

DNA variation at the FGF20 gene has been associated with Parkinson's disease (PD). In particular, SNP rs12720208 in the 3' untranslated region (3' UTR) was linked to PD-risk through a mechanism that would implicate a differential binding to microRNA-433 (miR-433). The reduction of the affinity of miR-433 to the 3' UTR would result in increased FGF20 expression and upregulation of alpha-synuclein, which could in...

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PMID: 20471450
DOI: 10.1016/j.neulet.2010.05.019

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FGF20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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