Article
Association study of B-cell marker gene polymorphisms in European Caucasian patients with systemic sclerosis.
Clinical and experimental rheumatology - 1 Jan 2000
Dawidowicz Karen, Dieudé Philippe, Avouac Jérôme, Wipff Julien, Hachulla Eric, Diot Elisabeth, Tiev Kiet, Cracowski Jean-Luc, Mouthon Luc, Amoura Zahir, Frances Camille, Carpentier Patrick, Meyer Olivier, Kahan André, Boileau Catherine, Allanore Yannick
Abstract excerpt
BACKGROUND: BANK1 and BLK B-cell genetic markers have been reproducibly and convincingly found to contribute to susceptibility to systemic sclerosis (SSc). OBJECTIVES: To determine whether other B-cell genetic markers including CD19, CD20, CD22 and CD24 polymorphisms affect susceptibility to SSc in the European Caucasian population. METHODS: A case-control study was performed in 900 patients with SSc and 1034...
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