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Article

Impact of pepsinogen C polymorphism on individual susceptibility to gastric cancer and its precancerous conditions in a Northeast Chinese population.

Journal of cancer research and clinical oncology - 1 Aug 2009

Sun Li-Ping, Guo Xiao-Lin, Zhang Ye, Chen Wei, Bai Xue-Lei, Liu Jin, Yuan Yuan

Abstract excerpt

PURPOSE: Human pepsinogen C (PGC) is an aspartic protease produced specifically by the gastric mucosa, and is considered as a mature marker of gastric epithelium. This study examined the contributions of PGC polymorphisms and the Helicobacter pylori (H. pylori) infection to the risk of gastric cancer (GC), and its precancerous conditions in a Northeast Chinese population. METHODS: The PGC insertion/deletion...

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Source

Identifiers

PMID: 19132389
DOI: 10.1007/s00432-008-0539-3

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Impact of pepsinogen C polymorphism on individual susceptibility to gastric cancer and its precancerous conditions in a Northeast Chinese population.PMID 19132389Read ↗

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