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Article

Correlation between negative expression of pepsinogen C and a series of phenotypic markers of gastric cancer in different gastric diseases.

Cancer medicine - 1 Aug 2018

Jiang Jingyi, Shen Shixuan, Dong Nannan, Liu Jingwei, Xu Qian, Sun Liping, Yuan Yuan

Abstract excerpt

Gastric tumorigenesis is a multistep process initiated by chronic superficial gastritis (SG), followed by atrophic gastritis (AG), then intestinal metaplasia (IM), and finally by dysplasia and adenocarcinoma according to the Correa model. Pepsinogen C (PGC) decreases gradually during progression of cancer, which makes PGC an ideal negative marker for GC. To explore the correlation between PGC and other positive...

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Identifiers

PMID: 29963765
DOI: 10.1002/cam4.1615
PMCID: PMC6089156

Genes

PGC
MMP9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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