Article
Gastric cancer in a Caucasian population: role of pepsinogen C genetic variants.
World journal of gastroenterology - 21 Aug 2006
Pinto-Correia Ana L, Sousa Hugo, Fragoso Maria, Moreira-Dias Luís, Lopes Carlos, Medeiros Rui, Dinis-Ribeiro Mário
Abstract excerpt
AIM: To study the role of an insertion/deletion polymorphism in the pepsinogen C (PGC) gene, an effective marker for terminal differentiation of the stomach mucosa, in the susceptibility to the development of gastric lesions. METHODS: The study was performed with 99 samples of known gastric lesions and 127 samples without evidence of neoplastic disease. PCR was employed and the 6 polymorphic alleles were...
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