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Article

Premature Aging of T cells Is Associated With Faster HIV-1 Disease Progression

20 Jan 2009

Abstract excerpt

OBJECTIVE: To determine if untreated HIV-1 infection and progression is associated with premature aging of memory CD8 and CD4 T cells and naive CD4 T cells. METHODS: Twenty HIV-1-infected fast progressors and 40 slow progressors were included in our study, using risk set sampling. The expression of cell surface markers reflecting the differentiation stages of lymphocytes was measured using flow cytometry analyses...

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PMID: 19131896
DOI: 10.1097/qai.0b013e3181926c28

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