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Article

The pro-fibrotic factor IGFBP-5 induces lung fibroblast and mononuclear cell migration.

American journal of respiratory cell and molecular biology - 1 Aug 2009

Yasuoka Hidekata, Yamaguchi Yukie, Feghali-Bostwick Carol A

Abstract excerpt

We have previously shown that insulin-like growth factor-binding protein-5 (IGFBP-5) is overexpressed in fibrotic lung tissues and that it induces production of extracellular matrix components such as collagen and fibronectin both in vitro and in vivo. We recently observed mononuclear cell infiltration in lung tissues of mice expressing IGFBP-5. We therefore examined the role of IGFBP-5 on the migration of immune...

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Source

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Identifiers

PMID: 19131643
DOI: 10.1165/rcmb.2008-0211OC
PMCID: PMC2715907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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