Article
Genomic sequence encoding diversity segments of the pig TCR delta chain gene demonstrates productivity of highly diversified repertoire.
Molecular immunology - 1 Mar 2009
Uenishi Hirohide, Eguchi-Ogawa Tomoko, Toki Daisuke, Morozumi Takeya, Tanaka-Matsuda Maiko, Shinkai Hiroki, Yamamoto Ryuji, Takagaki Yohtaroh
Abstract excerpt
To better understand the function and diversity of gammadelta T cells, we determined the genomic sequence encoding diversity (D) segments of the porcine TCR delta chain and its upstream regions, because pigs and other artiodactyls have relatively high proportions of gammadelta T cells. The revealed sequence contained 28 variable (V) alpha/delta segments, including 4 TRDV1 and at least 6 Ddelta segments, a much...
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