Article

Generation and first characterization of TRDC-Knockout pigs lacking γδ T cells

2021-03-29

Abstract excerpt

The TRDC-Locus encodes the T cell receptor delta constant region, one component of the γδ T cell receptor which is essential for development of γδ T cells. In contrast to peptide recognition by αβ T cells, antigens activating γδ T cells are mostly MHC independent and not well characterized. Therefore, the function of γδ T cells and their contribution to protection against infections is still unclear. Higher number...

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Literature Corpus work: 0406f2b0-4556-5549-aa02-b8b36f4b7b58
DOI: 10.1101/2021.03.27.437312

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