Article
Development of a RACE-based RNA-Seq approach to characterize the T-cell receptor repertoire of porcine γδ T cells.
Developmental and comparative immunology - 1 Apr 2020
Hammer Sabine E, Leopold Melanie, Prawits Lisa-Maria, Mair Kerstin H, Schwartz John C, Hammond John A, Ravens Sarina, Gerner Wilhelm, Saalmüller Armin
Abstract excerpt
Recent data suggest that porcine γδ T cells exhibit a similar degree of functional plasticity as human and murine γδ T cells. Due to the high frequency of TCR-γδ+ cells in blood and secondary lymphatic organs, the pig is an attractive model to study these cells, especially their combined features of the innate and the adaptive immune system. Using a 5' RACE-like approach, we translated a human/murine NGS library...
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