Article
QTLRel: an R package for genome-wide association studies in which relatedness is a concern.
BMC genetics - 27 Jul 2011
Cheng Riyan, Abney Mark, Palmer Abraham A, Skol Andrew D
Abstract excerpt
BACKGROUND: Existing software for quantitative trait mapping is either not able to model polygenic variation or does not allow incorporation of more than one genetic variance component. Improperly modeling the genetic relatedness among subjects can result in excessive false positives. We have developed an R package, QTLRel, to enable more flexible modeling of genetic relatedness as well as covariates and...
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