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Article

Hedgehog signalling is required for cloacal development in the zebrafish embryo.

The International journal of developmental biology - 1 Jan 2009

Parkin Caroline A, Allen Claire E, Ingham Philip W

Abstract excerpt

The Hedgehog (Hh) family of signalling molecules is essential for a wide range of developmental processes. Mammalian studies have implicated the Hedgehog pathway in the aetiology of anorectal malformations (ARMs), relatively common congenital anomalies caused by failures in the development of the cloaca. In this study we demonstrate that Hh signalling is absolutely required for the formation of the zebrafish...

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Identifiers

PMID: 19123126
DOI: 10.1387/ijdb.082669cp

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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