Gene expression profiles stratified according to type 1 diabetes mellitus susceptibility regions.

doi:10.1196/annals.1447.064

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Article

Gene expression profiles stratified according to type 1 diabetes mellitus susceptibility regions.

Annals of the New York Academy of Sciences - 1 Dec 2008

Rassi Diane Meyre, Junta Cristina Moraes, Fachin Ana Lúcia, Sandrin-Garcia Paula, Mello Stephano, Silva Guilherme Liberato, Evangelista Adriane Feijó, Magalhães Danielle Aparecida, Wastowski Isabela Jubé, Crispim Janaína Oliveira, Martelli-Palomino Gustavo, Fernandes Ana Paula Mores, Deghaide Neife N H S, Foss-Freitas Maria Cristina, Foss Milton César, Soares Christiane Pienna, Sakamoto-Hojo Elza Tieme, Passos Geraldo Aleixo Silva, Donadi Eduardo Antônio

Abstract excerpt

The MHC region (6p21) aggregates the major genes that contribute to susceptibility to type 1 diabetes (T1D). Three additional relevant susceptibility regions mapped on chromosomes 1p13 (PTPN22), 2q33 (CTLA-4), and 11p15 (insulin) have also been described by linkage studies. To evaluate the contribution of these susceptibility regions and the chromosomes that house these regions, we performed a large-scale...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19120314
DOI: 10.1196/annals.1447.064

Genes

PTPN22

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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