Article
Inducibility of the SOS response in a recA730 or recA441 strain is restored by transformation with a new recA allele.
Molecular & general genetics : MGG - 1 Aug 1993
Cazaux C, Mazard A M, Defais M
Abstract excerpt
Escherichia coli RecA protein plays an essential role in both genetic recombination and SOS repair; in vitro RecA needs to bind ATP to promote both activities. Residue 264 is involved in this interaction; we have therefore created two new recA alleles, recA664 (Tyr264-->Glu) and recA665 (Tyr264-->His) bearing mutations at this site. As expected both mutations affected all RecA activities in vivo. Complementation...
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