Article
[Hepatitis B virus genetic diversity and mutant].
The Korean journal of hepatology - 1 Dec 2008
Yim Hyung Joon
Abstract excerpt
Hepatitis B virus (HBV) is a partially double stranded DNA virus with genetic diversity represented by eight genotypes (A to H). Natural course and response to treatment could be affected by HBV genotypes. HBV shows high rates of turn over in the absence of proof-reading ability. As a result, large amounts of quasispecies are produced naturally or antiviral-associated. HBV consists of four open reading frames,...
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