Evidence for the involvement of endogenous thymidine in the density-inhibition of tumorigenic Chinese hamster V79 cells.

doi:10.1016/0167-4889(91)90085-c

Back to search

Article

Evidence for the involvement of endogenous thymidine in the density-inhibition of tumorigenic Chinese hamster V79 cells.

Biochimica et biophysica acta - 24 Sept 1991

Nakano S, Koga T, Ichinose I, Yamada H, Niho Y

Abstract excerpt

Two distinct low-molecular-weight growth inhibitory activities were isolated from supernatants of a density-inhibited, tumorigenic V79 Chinese hamster cell line. By chromatographic analyses, one of these was purified to homogeneity and eventually proved to be thymidine (dThd). In order to investi...

Topics

Animals
Cell Count
Cell Division
Cell Survival
Chromatography, High Pressure Liquid
Cricetinae
Cricetulus
Growth Inhibitors
Mutation
Thymidine
Tumor Cells, Cultured

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.