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Article

Evaluation of high-resolution melting analysis for screening the LDL receptor gene.

Clinical biochemistry - 1 Apr 2009

Laurie Andrew D, George Peter M

Abstract excerpt

OBJECTIVES: High-resolution melting analysis has been validated for screening several genes of clinical significance. We evaluated whether it would be useful for detecting mutations in the LDL receptor gene (LDLR). DESIGN AND METHODS: We analysed 60 samples heterozygous for different LDLR sequence variants, and compared the melting curves to those of the corresponding homozygous normal amplicons to assess whether...

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Source

Identifiers

PMID: 19118540
DOI: 10.1016/j.clinbiochem.2008.11.015

Genes

LDLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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