Article
Matrix metalloproteinase-2 polymorphism is associated with prognosis in prostate cancer.
Urologic oncology - 1 Jan 2000
dos Reis Sabrina Thalita, Villanova Fabiola Elizabeth, Andrade Priscila Maria, Pontes José, de Sousa-Canavez Juliana Moreira, Sañudo Adriana, Antunes Alberto Azoubel, Dall'oglio Marcos Francisco, Srougi Miguel, Moreira Leite Katia Ramos
Abstract excerpt
OBJECTIVE: Prostate cancer (PCa) is the most frequent tumor in males in Brazil. Single nucleotide polymorphisms (SNP) have been demonstrated in the promoter region of matrix metalloproteinases (MMPs) genes and have been associated with development and progression of some cancers. In this study, our aim was to investigate a possible relation between polymorphism of the promoter region of the MMP2 gene and...
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